The relationship between stress and digestive health is well-established, with stress being a common trigger for digestive disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). In this in-depth article, leading gastroenterologists and psychologists delve into the complex interplay between stress and digestive disorders, highlighting the physiological mechanisms involved and the impact of stress management techniques on symptom relief and disease management. Readers will gain insights into the mind-body connection in digestive health and practical strategies for addressing stress to support digestive wellness and overall quality of life.